
Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out the functions of normal cells and do not develop into healthy lung tissue. As they grow, the abnormal cells can form tumors and impede the function of the lung, which is to provide oxygen to the body via the blood.
The Genetic Basis of Lung Cancer
All cells in the body contain DNA. Every time a mature cell divides into two daughter cells, it replicates its DNA exactly. The daughter cells are clones of the original cell, identical in every way. It is in this way that our bodies continually replenish themselves. Old cells die off and the next generation takes their place.
A cancer begins with an error, or mutation, in a cell's DNA. DNA mutations can be caused by the normal aging process or through environmental factors, such as cigarette smoke or breathing in asbestos.
Lung Cancer Statistics
Lung cancer is one of the most common cancers. It is the second most diagnosed cancer in men and women (after prostate and breast, respectively), but it is the number one cause of death from cancer each year in both men and women. Because lung cancer can take years to develop, it is mostly found in older people. The average age of a person receiving a lung cancer diagnosis is 69 years.
Overall, lung cancer affects men more than women, but that gap is closing.
Cigarette smoking is the cause of most lung cancers, but there are other factors, too. Exposure to asbestos, radon, environmental factors, or secondhand smoke can cause lung cancer. There are often internal factors (inherited or from our genes) as well as external or environmental factors (from outside of our bodies) involved in the development of any type of cancer.
Lung Cancer Symptoms
The signs and symptoms of lung cancer can take years to develop and they may not appear until the disease is advanced.
Some symptoms of lung cancer that are in the chest:
Intense coughing
Pain in the chest, shoulder, or back
A change in color or volume of sputum
Shortness of breath
Changes in the voice or being hoarse
Recurrent lung problems, such as bronchitis or pneumonia
Coughing up phlegm or mucus, especially if it is tinged with blood
Coughing up blood
If the original lung cancer has spread, a person may feel symptoms in other places in the body. Common places for lung cancer to spread include other parts of the lungs, lymph nodes, bones, brain, liver, and adrenal glands.
Some symptoms of lung cancer that may occur elsewhere in the body:
Loss of appetite or unexplained weight loss
Fatigue
Headaches, bone or joint pain
Bone fractures not related to accidental injury
Neurological symptoms, such as memory loss
General weakness
If you are at risk for developing lung cancer
If you are a current or former smoker, have been exposed to asbestos, radon, other environmental factors, secondhand smoke, or have a family member who developed lung cancer but who did not have those risk factors, then you may be at increased risk of developing lung cancer.
If you are at risk of developing lung cancer, the most important thing you can do is to quit smoking (if you smoke). Because smoking can cause cancers other than lung cancer, such as cancers of the esophagus, pancreas, larynx, bladder, and others, stopping smoking will reduce your risk of developing those cancers, too. Research shows that smoking cessation has many benefits that are apparent soon after quitting, such as lowered blood pressure and increased lung capacity. Depending on how long and how much you smoked, quitting may not completely erase your risk of developing lung cancer, but it will definitely reduce the risk.
Because environmental factors other than smoking can increase your risk of lung cancer, it is important to reduce or eliminate those factors. Examples of environmental factors include asbestos, radon, and secondhand smoke. If you have been exposed to asbestos or radon, you can take steps to decrease or eliminate those exposures.
If you have lung cancer
Even if you have been diagnosed with lung cancer, lifestyle changes can help you manage symptoms of the disease and your treatment.
Smoking causes the majority of lung cancers. By quitting smoking, you can immediately gain some benefits from enhanced circulation, lowered blood pressure, and increased lung function. These benefits will help your body better tolerate and heal from surgery, chemotherapy, or radiation treatment.
All cells in the body contain DNA. Every time a mature cell divides into two daughter cells, it replicates its DNA exactly. The daughter cells are clones of the original cell, identical in every way. It is in this way that our bodies continually replenish themselves. Old cells die off and the next generation takes their place.
A cancer begins with an error, or mutation, in a cell's DNA. DNA mutations can be caused by the normal aging process or through environmental factors, such as cigarette smoke or breathing in asbestos.
Lung Cancer Statistics
Lung cancer is one of the most common cancers. It is the second most diagnosed cancer in men and women (after prostate and breast, respectively), but it is the number one cause of death from cancer each year in both men and women. Because lung cancer can take years to develop, it is mostly found in older people. The average age of a person receiving a lung cancer diagnosis is 69 years.
Overall, lung cancer affects men more than women, but that gap is closing.
Cigarette smoking is the cause of most lung cancers, but there are other factors, too. Exposure to asbestos, radon, environmental factors, or secondhand smoke can cause lung cancer. There are often internal factors (inherited or from our genes) as well as external or environmental factors (from outside of our bodies) involved in the development of any type of cancer.
Lung Cancer Symptoms
The signs and symptoms of lung cancer can take years to develop and they may not appear until the disease is advanced.
Some symptoms of lung cancer that are in the chest:
Intense coughing
Pain in the chest, shoulder, or back
A change in color or volume of sputum
Shortness of breath
Changes in the voice or being hoarse
Recurrent lung problems, such as bronchitis or pneumonia
Coughing up phlegm or mucus, especially if it is tinged with blood
Coughing up blood
If the original lung cancer has spread, a person may feel symptoms in other places in the body. Common places for lung cancer to spread include other parts of the lungs, lymph nodes, bones, brain, liver, and adrenal glands.
Some symptoms of lung cancer that may occur elsewhere in the body:
Loss of appetite or unexplained weight loss
Fatigue
Headaches, bone or joint pain
Bone fractures not related to accidental injury
Neurological symptoms, such as memory loss
General weakness
If you are at risk for developing lung cancer
If you are a current or former smoker, have been exposed to asbestos, radon, other environmental factors, secondhand smoke, or have a family member who developed lung cancer but who did not have those risk factors, then you may be at increased risk of developing lung cancer.
If you are at risk of developing lung cancer, the most important thing you can do is to quit smoking (if you smoke). Because smoking can cause cancers other than lung cancer, such as cancers of the esophagus, pancreas, larynx, bladder, and others, stopping smoking will reduce your risk of developing those cancers, too. Research shows that smoking cessation has many benefits that are apparent soon after quitting, such as lowered blood pressure and increased lung capacity. Depending on how long and how much you smoked, quitting may not completely erase your risk of developing lung cancer, but it will definitely reduce the risk.
Because environmental factors other than smoking can increase your risk of lung cancer, it is important to reduce or eliminate those factors. Examples of environmental factors include asbestos, radon, and secondhand smoke. If you have been exposed to asbestos or radon, you can take steps to decrease or eliminate those exposures.
If you have lung cancer
Even if you have been diagnosed with lung cancer, lifestyle changes can help you manage symptoms of the disease and your treatment.
Smoking causes the majority of lung cancers. By quitting smoking, you can immediately gain some benefits from enhanced circulation, lowered blood pressure, and increased lung function. These benefits will help your body better tolerate and heal from surgery, chemotherapy, or radiation treatment.
Types of Treatment
Surgery
Curative surgery: The removal of a tumor when it appears to be confined to one area, which means an early stage cancer. This type of surgery aims to completely remove the cancerous tumor, and may include remove a wedge, a lobe, or an entire lung.
Palliative surgery: The goal of this surgery is to make the patient more comfortable, e.g., laser surgery for the removal of an obstruction or opening of an airway.
Chemotherapy : Chemotherapy uses strong chemicals or drugs to kill cancer cells, stop their reproduction, or slow their growth.
Radiation: Radiation therapy (also called radiotherapy) may be effective for the treatment of lung cancer. It uses high-energy rays, similar to X-rays, but stronger, to kill or shrink cancer cells.
Surgery
Curative surgery: The removal of a tumor when it appears to be confined to one area, which means an early stage cancer. This type of surgery aims to completely remove the cancerous tumor, and may include remove a wedge, a lobe, or an entire lung.
Palliative surgery: The goal of this surgery is to make the patient more comfortable, e.g., laser surgery for the removal of an obstruction or opening of an airway.
Chemotherapy : Chemotherapy uses strong chemicals or drugs to kill cancer cells, stop their reproduction, or slow their growth.
Radiation: Radiation therapy (also called radiotherapy) may be effective for the treatment of lung cancer. It uses high-energy rays, similar to X-rays, but stronger, to kill or shrink cancer cells.



